BAPTA AM

BAPTA AM
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15551-5 5 mg -

6 - 10 business days*

52.00€
Cay15551-10 10 mg -

6 - 10 business days*

86.00€
Cay15551-25 25 mg -

6 - 10 business days*

139.00€
Cay15551-100 100 mg -

6 - 10 business days*

497.00€
 
BAPTA (Cay-11706) is membrane-impermeable calcium chelator that binds extracellular calcium ions... more
Product information "BAPTA AM"
BAPTA (Cay-11706) is membrane-impermeable calcium chelator that binds extracellular calcium ions (Kd = 0.11 µM), with selectivity over magnesium ions or protons. BAPTA and its derivatives can also be used as calcium indicators, since the absorption maximum for BAPTA changes when it is complexed with calcium (absorption maxima free/complexed = 254/274 nm, emission maxima free/complexed = 363/363 nm). BAPTA AM is a cell permeable analog of BAPTA that binds calcium only after the acetoxymethyl group is removed by cytoplasmic esterases. It is commonly used at 10-100 µM to evaluate the role of intracellular calcium in cell signaling. It can also be used in animals. BAPTA AM also inhibits voltage-gated potassium (Kv) channels, including Kv1.3, Kv1.5, and Kv11.1 (Ki = 1.45, 1.23, and 1.30 µM, respectively).Formal Name: N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-1,1'-bis[(acetyloxy)methyl] ester-glycine. CAS Number: 126150-97-8. Synonyms: BAPTA Acetoxymethyl ester. Molecular Formula: C34H40N2O18. Formula Weight: 764.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 213, 248, 286 nm. SMILES: O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)C1=CC=CC=C1OCCOC2=CC=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O. InChi Code: InChI=1S/C34H40N2O18/c1-23(37)47-19-51-31(41)15-35(16-32(42)52-20-48-24(2)38)27-9-5-7-11-29(27)45-13-14-46-30-12-8-6-10-28(30)36(17-33(43)53-21-49-25(3)39)18-34(44)54-22-50-26(4)40/h5-12H,13-22H2,1-4H3. InChi Key: YJIYWYAMZFVECX-UHFFFAOYSA-N.
Keywords: BAPTA Acetoxymethyl ester, N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-[2-[(acetyloxy)methoxy]-2-oxoethyl]-1,1'-bis[(acetyloxy)methyl] ester-glycine
Supplier: Cayman Chemical
Supplier-Nr: 15551

Properties

Application: Cell permeable calcium chelator
MW: 764.7 D
Formula: C34H40N2O18
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 126150-97-8| Matching products
KEGG ID : K04935 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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