Valeroyl Salicylate

Valeroyl salicylate is a selective, irreversible inhibitor of cyclooxygenase-1 (COX-1). The IC50 values for ovine COX-1 and -2 are 0.8 and 15 mM, respectively. The half-lives for inactivation of human recombinant and ovine COX-1 in the presence of 500 µM valeroyl salicylate are 12 and 45 minutes, respectively.Formal Name: 2-[(1-oxopentyl)oxy]-benzoic acid. CAS Number: 64206-54-8. Synonyms: 2-Valeryloxybenzoic Acid. Molecular Formula: C12H14O4. Formula Weight: 222.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMSO: 40 mg/ml, Ethanol: 50 mg/ml, PBS pH 7.2: 5 mg/ml. SMILES: CCCCC(=O)Oc1ccccc1C(=O)O. InChi Code: InChI=1S/C12H14O4/c1-2-3-8-11(13)16-10-7-5-4-6-9(10)12(14)15/h4-7H,2-3,8H2,1H3,(H,14,15). InChi Key: WJHZBTMHUNVIKC-UHFFFAOYSA-N.