(±)-trans-ACPD

(±)-trans-ACPD
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay28849-1 1 mg -

6 - 10 business days*

50.00€
Cay28849-5 5 mg -

6 - 10 business days*

156.00€
Cay28849-10 10 mg -

6 - 10 business days*

286.00€
Cay28849-25 25 mg -

6 - 10 business days*

649.00€
 
(±)-trans-ACPD is an agonist of metabotropic glutamate receptors (mGluRs, EC50s = 15, 2, 40, 23,... more
Product information "(±)-trans-ACPD"
(±)-trans-ACPD is an agonist of metabotropic glutamate receptors (mGluRs, EC50s = 15, 2, 40, 23, and 82 µM for mGluR1, -2, -3, -5, and -6, respectively, in CHO cells expressing recombinant receptors). It also activates mGluR4 in baby hamster kidney cells with an EC50 value of approximately 800 µM. (±)-trans-ACPD increases cAMP accumulation in adult rat cerebral cortex slices (EC50 = 47.8 µM) but not in isolated rat embryonic neurons or neonatal glial cells when used at concentrations ranging from 1 to 1,000 µM. (±)-trans-ACPD (10-1,000 µM) increases phosphoinositide hydrolysis in neonatal rat cerebral cortex and hippocampal slices. It induces clonic convulsions in neonatal rats (ED50 = 100 mg/kg), an effect that can be reversed by administration of the NMDA receptor antagonists LY233053 and LY274614.Formal Name: (1R,3S)-1-aminocyclopentane-1,3-dicarboxylic acid. CAS Number: 67684-64-4. Molecular Formula: C7H11NO4. Formula Weight: 173.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: soluble, Water: slightly soluble. SMILES: OC([C@H]1CC[C@@](C(O)=O)(N)C1)=O. InChi Code: InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7+/m0/s1. InChi Key: YFYNOWXBIBKGHB-MHTLYPKNSA-N.
Keywords: (1R,3S)-1-aminocyclopentane-1,3-dicarboxylic acid
Supplier: Cayman Chemical
Supplier-Nr: 28849

Properties

Application: mGluR agonist
MW: 173.2 D
Formula: C7H11NO4
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 67684-64-4| Matching products
KEGG ID : K04603 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "(±)-trans-ACPD"
Write a review
or to review a product.
Viewed