TMPyP4 (tosylate)

TMPyP4 (tosylate)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay18474-50 50 mg -

6 - 10 business days*

50.00€
Cay18474-100 100 mg -

6 - 10 business days*

92.00€
Cay18474-250 250 mg -

6 - 10 business days*

216.00€
Cay18474-500 500 mg -

6 - 10 business days*

379.00€
 
TMPyP4 is a cationic porphyrin that intercalates into and stabilizes G-quadruplexes, which are... more
Product information "TMPyP4 (tosylate)"
TMPyP4 is a cationic porphyrin that intercalates into and stabilizes G-quadruplexes, which are formed by DNA and RNA sequences composed of blocks of guanine residues. In this way, TMPyP4 inhibits telomerase activity (IC50 = 50 µM), blocking the clonogenic growth and migration of cancer cells in culture and in vivo. TMPyP4 also inhibits acetylcholinesterase at doses of 0.1 to 1.0 mM.Formal Name: 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-methyl-pyridinium], 4-methylbenzenesulfonate (1:4). CAS Number: 36951-72-1. Synonyms: TMP-1363, TMPyP4 4-methylbenzenesulfonate. Molecular Formula: C44H38N8 . 4C7H7O3S. Formula Weight: 1363.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 219, 261, 423 nm. SMILES: C[N+]1=CC=C(/C2=C3N/C(C=C/3)=C(C4=N/C(C=C4)=C(C5=CC=C(/C(C6=CC=[N+](C=C6)C)=C7C=CC2=N/7)N5)/C8=CC=[N+](C=C8)C)/C9=CC=[N+](C=C9)C)C=C1.CC%10=CC=C(C=C%10)S([O-])(=O)=O.CC%11=CC=C(C=C%11)S([O-])(=O)=O.CC%12=CC=C(C=C%12)S([O-])(=O)=O.CC%13=CC=C(C=C%13)S(. InChi Code: InChI=1S/C44H37N8.4C7H8O3S/c1-49-21-13-29(14-22-49)41-33-5-7-35(45-33)42(30-15-23-50(2)24-16-30)37-9-11-39(47-37)44(32-19-27-52(4)28-20-32)40-12-10-38(48-40)43(36-8-6-34(41)46-36)31-17-25-51(3)26-18-31,4*1-6-2-4-7(5-3-6)11(8,9)10/h5-28H,1-4H3,(H,45,4. InChi Key: AKZFRMNXBLFDNN-GVHKZQBISA-K.
Keywords: TMP-1363, TMPyP4 4-methylbenzenesulfonate, 4,4',4'',4'''-(21H,23H-porphine-5,10,15,20-tetrayl)tetrakis[1-methyl-pyridinium], 4-methylbenzenesulfonate (1:4)
Supplier: Cayman Chemical
Supplier-Nr: 18474

Properties

Application: G-quadruplex stabilizer, Telomerase inhibitor
MW: 1363.6 D
Formula: C44H38N8 . 4C7H7O3S
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 36951-72-1| Matching products
KEGG ID : K11126 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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