Ruxolitinib
COVID-19 Research
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
White to off-white solid. Soluble in DMSO or ethanol. Insoluble in water. Antineoplastic,... more
Product information "Ruxolitinib"
White to off-white solid. Soluble in DMSO or ethanol. Insoluble in water. Antineoplastic, anti-inflammatory and immunomodulating agent, Orally bioavailable potent ATP mimetic that inhibits both JAK1 and JAK2 with IC50 values of 2.7 and 4.5nM, respectively and is less selective for JAK3 (IC50 = 322nM), Affects DC differentiation and function, leading to impaired T cell activation, Used in the treatment of myeloproliferative neoplasms and psoriasis, Anticancer agent. Shown to induce apoptosis and autophagy, Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro.
| Keywords: | INCB018424, INC 424 |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-CR1-3624 |
Properties
| Application: | JAK1 inhibitor, JAK2 inhibitor |
| MW: | 306,4 D |
| Formula: | C17H18N6 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 941678-49-5| Matching products |
| KEGG ID : | K11217 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H302, H315, H319, H361, H373 |
| P Phrases: | P260, P280, P301+P312, P302+P352, P305+P351+P338, P308+P313, P405 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed