RC574

RC574
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay31408-1 1 mg -

6 - 10 business days*

77.00€
Cay31408-5 5 mg -

6 - 10 business days*

279.00€
Cay31408-10 10 mg -

6 - 10 business days*

477.00€
 
RC574 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic... more
Product information "RC574"
RC574 is an inhibitor of ferroptosis and a derivative of the antioxidant and hypocholesterolemic agent probucol (Cay-15043). It inhibits glutamate-induced cell death in HT22 cells (IC50 = 276.2 nM) and mouse primary cortical neurons when used at a concentration of 3 µM. RC574 (3 µM) increases glutathione peroxidase 1 (GPX1) levels and GPX activity, as well as inhibits glutamate-induced mitochondrial superoxide anion production, in HT22 cells. It completely inhibits ferroptosis induced by the GPX4 inhibitor RSL3 in HT22 cells when used at concentrations ranging from 62.5 to 1,000 nM.Formal Name: 2,6-bis(1,1-dimethylethyl)-4-(2-thienylseleno)-phenol. CAS Number: 2584411-87-8. Molecular Formula: C18H24OSSe. Formula Weight: 367.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 239 nm. SMILES: OC1=C(C(C)(C)C)C=C([Se]C2=CC=CS2)C=C1C(C)(C)C. InChi Code: InChI=1S/C18H24OSSe/c1-17(2,3)13-10-12(21-15-8-7-9-20-15)11-14(16(13)19)18(4,5)6/h7-11,19H,1-6H3. InChi Key: CUSKUKDTRDQWBN-UHFFFAOYSA-N.
Keywords: 2,6-bis(1,1-dimethylethyl)-4-(2-thienylseleno)-phenol
Supplier: Cayman Chemical
Supplier-Nr: 31408

Properties

Application: Ferroptosis inhibitor
MW: 367.4 D
Formula: C18H24OSSe
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 2584411-87-8| Matching products
KEGG ID : K00432 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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