(-)-Rasfonin

(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus. It inhibits proliferation of mouse splenocytes induced by concanavalin A (Cay-14951) and LPS (IC50s = 0.7 and 0.5 µg/ml, respectively).Formal Name: (2E,4E,6S)-8-hydroxy-6-(hydroxymethyl)-4-methyl-2,4-octadienoic acid, (2R,3R)-3,6-dihydro-6-oxo-2-[(1S,3R,5E)-1,3,5-trimethyl-5-hepten-1-yl]-2H-pyran-3-yl ester. CAS Number: 303156-68-5. Synonyms: TT-1. Molecular Formula: C25H38O6. Formula Weight: 434.6. Purity: >95%. Formulation: (Request formulation change), A liquid. Solubility: DMSO: 1 mg/ml, Ethanol: Soluble, Methanol: Soluble. SMILES: O=C1O[C@@]([C@@H](C)C[C@@H](C)C/C(C)=C/C)([H])[C@H](OC(/C=C/C(C)=C/[C@@H](CO)CCO)=O)C=C1. InChi Code: InChI=1S/C25H38O6/c1-6-17(2)13-19(4)14-20(5)25-22(8-10-24(29)31-25)30-23(28)9-7-18(3)15-21(16-27)11-12-26/h6-10,15,19-22,25-27H,11-14,16H2,1-5H3/b9-7+,17-6+,18-15+/t19-,20-,21-,22+,25+/m0/s1. InChi Key: OHRGHFXATDKGOV-FXYCKZMJSA-N. Origin: Fungus/Trichurus sp..