PI3-Kinase alpha Inhibitor 2

PI3-Kinase alpha Inhibitor 2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010177-500 500 µg -

6 - 10 business days*

27.00€
Cay10010177-1 1 mg -

6 - 10 business days*

50.00€
Cay10010177-5 5 mg -

6 - 10 business days*

210.00€
Cay10010177-10 10 mg -

6 - 10 business days*

368.00€
 
PI3-Kinase alpha (PI3Kalpha) inhibitor 2 is an inhibitor of PI3K p110alpha (IC50 = 2 nM in an... more
Product information "PI3-Kinase alpha Inhibitor 2"
PI3-Kinase alpha (PI3Kalpha) inhibitor 2 is an inhibitor of PI3K p110alpha (IC50 = 2 nM in an enzyme assay). It is selective for p110alpha over p110beta, p110gamma, and PI3K C2beta (IC50s = 16, 660, and 220 nM, respectively). It also inhibits mammalian target of rapamycin (mTOR, IC50 = 49 nM). PI3Kalpha inhibitor 2 inhibits proliferation in A375 melanoma cells with an IC50 value of 0.58 µM. Formal Name: 3-[4-(4-morpholinyl)thieno[3,2-d]pyrimidin-2-yl-phenol. CAS Number: 371943-05-4. Synonyms: PI3Kalpha Inhibitor 2, Phosphatidylinositol 3-Kinase alpha Inhibitor 2. Molecular Formula: C16H15N3O2S. Formula Weight: 313.4. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH 7.2) (1:3): 0.25mg/ml, DMSO: 25 mg/ml, Ethanol: 1 mg/ml. lambdamax: 255, 299 nm. SMILES: Oc1cccc(c1)c1nc2ccsc2c(n1)N1CCOCC1. InChi Code: InChI=1S/C16H15N3O2S/c20-12-3-1-2-11(10-12)15-17-13-4-9-22-14(13)16(18-15)19-5-7-21-8-6-19/h1-4,9-10,20H,5-8H2. InChi Key: XXLAEKOWCYJOKK-UHFFFAOYSA-N.
Keywords: Phosphatidylinositol 3-Kinase alpha Inhibitor 2, PI3Kalpha Inhibitor 2, 3-[4-(4-morpholinyl)thieno[3,2-d]pyrimidin-2-yl-phenol
Supplier: Cayman Chemical
Supplier-Nr: 10010177

Properties

Application: PI3Kalpha inhibitor
MW: 313.4 D
Formula: C16H15N3O2S
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 371943-05-4| Find alternatives
KEGG ID : K00922 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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