Phorbol 12-myristate 13-acetate
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Most commonly-used phorbol ester, Binds to and activates protein kinase C (PKC) at nM... more
Product information "Phorbol 12-myristate 13-acetate"
Most commonly-used phorbol ester, Binds to and activates protein kinase C (PKC) at nM concentrations, Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16, Potent mouse skin tumor promoter, Promoter of inducible NOS (iNOS, NOS II), Apoptosis inducer, Potential effective cancer therapeutic agent, Inhibitor of anti-lipolytic activity of insulin. Semisynthetic.
| Keywords: | PMA, TPA, 12-O-Tetradecanoylphorbol 13-acetate |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-CN2-0010 |
Properties
| Application: | PKC activator |
| MW: | 616,8 D |
| Formula: | C36H56O8 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 16561-29-8| Matching products |
| KEGG ID : | K02677 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H312, H315 |
| P Phrases: | P270, P280 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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