PCI 24781

PCI 24781
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay20059-1 1 mg -

6 - 10 business days*

43.00€
Cay20059-5 5 mg -

6 - 10 business days*

134.00€
Cay20059-10 10 mg -

6 - 10 business days*

226.00€
Cay20059-25 25 mg -

6 - 10 business days*

510.00€
 
PCI 24781 is an HDAC inhibitor that predominantly targets HDAC1 with a Ki value of 7 nM. It... more
Product information "PCI 24781"
PCI 24781 is an HDAC inhibitor that predominantly targets HDAC1 with a Ki value of 7 nM. It inhibits HDAC2, HDAC3/SMRT, HDAC6, HDAC8, and HDAC10 with Ki values of 19, 8.2, 17, 280, and 24 nM, respectively. PCI 24781 can prevent the growth of tumor cells in vitro, inducing apoptosis, as well as in mice harboring HCT116 or DLD-1 colon tumor xenografts.Formal Name: 3-[(dimethylamino)methyl]-N-[2-[4-[(hydroxyamino)carbonyl]phenoxy]ethyl]-2-benzofurancarboxamide. CAS Number: 783355-60-2. Synonyms: CRA-024781, CRA-24781. Molecular Formula: C21H23N3O5. Formula Weight: 397.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 50 mg/ml, DMF:PBS (pH 7.2)(1:3): 0.1 mg/ml, DMSO: 30 mg/ml, Ethanol: 3 mg/ml. lambdamax: 265 nm. SMILES: O=C(NO)C1=CC=C(OCCNC(C2=C(CN(C)C)C3=C(C=CC=C3)O2)=O)C=C1. InChi Code: InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25). InChi Key: MAUCONCHVWBMHK-UHFFFAOYSA-N.
Keywords: CRA-024781, CRA-24781, 3-[(dimethylamino)methyl]-N-[2-[4-[(hydroxyamino)carbonyl]phenoxy]ethyl]-2-benzofurancarboxamide
Supplier: Cayman Chemical
Supplier-Nr: 20059

Properties

Application: Antineoplastic, HDAC inhibitor
MW: 397.4 D
Formula: C21H23N3O5
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 783355-60-2| Matching products
KEGG ID : K11404 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H361, H373
P Phrases: P201, P202, P260, P264, P270, P280, P301+310, P308+313, P314, P330, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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