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NHI 2 is an inhibitor of lactate dehydrogenase A (LDHA, IC50 = 14.7 µM). It is selective for LDHA over LDHB (IC50 = 55.8 µM). It inhibits lactate production in HeLa cells when used at concentrations of 100 and 200 µM. NHI 2 is cytotoxic to HeLa cells (IC50 = 33.4 µM).Formal Name: 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylic acid, methyl ester. CAS Number: 1269802-97-2. Molecular Formula: C17H12F3NO3. Formula Weight: 335.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 25 mg/ml, Ethanol: 25 mg/ml. lambdamax: 256, 322 nm. SMILES: ON1C(C(OC)=O)=CC(C1=C2)=C(C(F)(F)F)C=C2C3=CC=CC=C3. InChi Code: InChI=1S/C17H12F3NO3/c1-24-16(22)15-9-12-13(17(18,19)20)7-11(8-14(12)21(15)23)10-5-3-2-4-6-10/h2-9,23H,1H3. InChi Key: YPPFWRWCZNXINO-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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