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MJN228 is a selective ligand for the lipid-binding protein nucleobindin 1 (NUCB1), blocking binding of the probe arachidonoyl ethanolamide-diazirine with an IC50 value of 3.3 µM. It prevents probe binding to NUCB1 in Neuro2a cells at concentrations as low as 10 µM. MJN228 has been used to elucidate the role of NUCB1 in lipid metabolic pathways in cells.Formal Name: (4-methyl-1-piperazinyl)(5-nitro-3-phenyl-1H-indol-2-yl)-methanone. CAS Number: 459168-97-9. Molecular Formula: C20H20N4O3. Formula Weight: 364.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/mL, DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL, DMSO: 25 mg/mL. lambdamax: 278 nm. SMILES: O=C(N1CCN(C)CC1)C2=C(C3=CC=CC=C3)C4=CC([N+]([O-])=O)=CC=C4N2. InChi Code: InChI=1S/C20H20N4O3/c1-22-9-11-23(12-10-22)20(25)19-18(14-5-3-2-4-6-14)16-13-15(24(26)27)7-8-17(16)21-19/h2-8,13,21H,9-12H2,1H3. InChi Key: BLSWPPPBUQFKHH-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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