M435-1279

Item number	Size	Datasheet	Manual	SDS	Delivery time	Price
TGM-T9500-1mg	1 mg				7 - 10 business days*	30.00€
TGM-T9500-5mg	5 mg				7 - 10 business days*	69.00€
TGM-T9500-1mL	1 ml				7 - 10 business days*	82.00€
TGM-T9500-10mg	10 mg				7 - 10 business days*	109.00€
TGM-T9500-25mg	25 mg				7 - 10 business days*	210.00€
TGM-T9500-50mg	50 mg				7 - 10 business days*	314.00€
TGM-T9500-100mg	100 mg				7 - 10 business days*	444.00€
TGM-T9500-200mg	200 mg	-	-	-	7 - 10 business days*	625.00€

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Description: M435-1279 is a UBE2T inhibitor that blocks UBE2T-mediated degradation of RACK1,... more

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Product information "M435-1279"

Description: M435-1279 is a UBE2T inhibitor that blocks UBE2T-mediated degradation of RACK1, thereby inhibiting the hyperactivation of the Wnt/beta-catenin signaling pathway. Target: E1/E2/E3 Enzyme. Smiles: NS(=O)(=O)c1ccc(NC(=O)c2c(O)c3c4CCCCc4sc3[nH]c2=O)cc1. References: Yu Z, Jiang X, Qin L, Deng H, Wang J, Ren W, Li H, Zhao L, Liu H, Yan H, Shi W, Wang Q, Luo C, Long B, Zhou H, Sun H, Jiao Z. A novel UBE2T inhibitor suppresses Wnt/beta-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination. Oncogene. 2021 Feb,40(5):1027-1042. doi: 10.1038/s41388-020-01572-w. Epub 2020 Dec 15. Erratum in: Oncogene. 2021 Apr,40(14):2622-2623. PMID: 33323973, PMCID: PMC7862066.

Supplier:	TargetMol
Supplier-Nr:	T9500

Properties

MW:	419.47 D
Formula:	C18H17N3O5S2

Database Information

CAS :

1359431-16-5| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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