LED209

LED209
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16844-1 1 mg -

6 - 10 business days*

14.00€
Cay16844-5 5 mg -

6 - 10 business days*

63.00€
Cay16844-10 10 mg -

6 - 10 business days*

110.00€
Cay16844-50 50 mg -

6 - 10 business days*

482.00€
 
Bacterial pathogens require the conserved membrane histidine sensor kinase (QseC) to detect both... more
Product information "LED209"
Bacterial pathogens require the conserved membrane histidine sensor kinase (QseC) to detect both host-derived adrenergic signals and the bacterial autoinducer-3 (AI-3), thus activating a signaling cascade that induces virulence gene expression. LED209 is a potent QseC inhibitor that blocks both norepinephrine- and epinephrine-triggered QseC-dependent virulence gene expression at 5 pM in vitro. While LED209 inhibits virulence of enterohemorrhagic E. coli, S. typhimurium, and F. tularensis, it does not inhibit pathogen growth, a highly desirable feature of antimicrobial agents to prevent drug resistance. Formal Name: N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-benzenesulfonamide. CAS Number: 245342-14-7. Molecular Formula: C19H17N3O2S2. Formula Weight: 383.5. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 20 mg/ml, Ethanol: 0.15 mg/ml. lambdamax: 295 nm. SMILES: S=C(Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1)Nc1ccccc1. InChi Code: InChI=1S/C19H17N3O2S2/c23-26(24,22-17-9-5-2-6-10-17)18-13-11-16(12-14-18)21-19(25)20-15-7-3-1-4-8-15/h1-14,22H,(H2,20,21,25). InChi Key: HNDRSTUKPCLQLT-UHFFFAOYSA-N.
Keywords: N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-benzenesulfonamide
Supplier: Cayman Chemical
Supplier-Nr: 16844

Properties

Application: QseC inhibitor
MW: 383.5 D
Formula: C19H17N3O2S2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 245342-14-7| Find alternatives
KEGG ID : K07645 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "LED209"
Write a review
or to review a product.
Viewed