Kenpaullone

Kenpaullone
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010239-1 1 mg -

6 - 10 business days*

49.00€
Cay10010239-5 5 mg -

6 - 10 business days*

123.00€
Cay10010239-10 10 mg -

6 - 10 business days*

185.00€
Cay10010239-25 25 mg -

6 - 10 business days*

403.00€
 
The development of selective, cell-permeable protein kinase inhibitors for the treatment of... more
Product information "Kenpaullone"
The development of selective, cell-permeable protein kinase inhibitors for the treatment of cancer, inflammation, and other diseases, is a major focus of drug development efforts. Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK3beta). It inhibits GSK3beta with an IC50 value of 0.023 µM (0.23 µM) and Cdk1/cyclin B, Cdk2/cyclin A, Cdk5/p25, and lymphocyte kinase with IC50 values of 0.4, 0.68, 0.85, and 0.47 µM, respectively. Formal Name: 9-bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one. CAS Number: 142273-20-9. Synonyms: 9-Bromopaullone, NSC 664704. Molecular Formula: C16H11BrN2O. Formula Weight: 327.2. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 3 mg/ml, DMSO: 10 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 230, 320 nm. SMILES: O=C1Nc2ccccc2c2[nH]c3ccc(Br)cc3c2C1. InChi Code: InChI=1S/C16H11BrN2O/c17-9-5-6-14-11(7-9)12-8-15(20)18-13-4-2-1-3-10(13)16(12)19-14/h1-7,19H,8H2,(H,18,20). InChi Key: QQUXFYAWXPMDOE-UHFFFAOYSA-N.
Keywords: 9-Bromopaullone, NSC 664704, 9-bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
Supplier: Cayman Chemical
Supplier-Nr: 10010239

Properties

Application: CDK inhibitor, GSK-3 beta inhibitor
MW: 327.2 D
Formula: C16H11BrN2O
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 142273-20-9| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315, H319, H335
P Phrases: P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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