IQ-1

IQ-1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16153-5 5 mg -

6 - 10 business days*

142.00€
Cay16153-10 10 mg -

6 - 10 business days*

238.00€
Cay16153-25 25 mg -

6 - 10 business days*

554.00€
Cay16153-50 50 mg -

6 - 10 business days*

1,037.00€
 
IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that maintains long-term mouse... more
Product information "IQ-1"
IQ-1 is a cell-permeable tetrahydroisoquinolinylidene compound that maintains long-term mouse embryonic stem cell (ESC) pluripotency. When used at 4 µg/ml with Wnt3a, it allows ESCs to form embryoid bodies that continue to express markers of pluripotency, including alpha-fetoprotein and beta-III tubulin. IQ-1 blocks the interaction of the protein Naked cuticle with a subunit of the protein phosphatase PP2A, altering signaling through Wnt/beta-catenin and maintaining the expression of stem cell markers Oct4, Nanog, and Rex1 in ESCs.Formal Name: 2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide. CAS Number: 331001-62-8. Molecular Formula: C21H22N4O2. Formula Weight: 362.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 25 mg/ml, Ethanol: 10 mg/ml. lambdamax: 230, 248, 368 nm. SMILES: CC(N/1)(C)CC2=CC=CC=C2C1=C(\N=N\C3=CC=C(C(C)=O)C=C3)C(N)=O. InChi Code: InChI=1S/C21H22N4O2/c1-13(26)14-8-10-16(11-9-14)24-25-19(20(22)27)18-17-7-5-4-6-15(17)12-21(2,3)23-18/h4-11,23H,12H2,1-3H3,(H2,22,27)/b19-18-,25-24+. InChi Key: ZXSRRUROLCGTBS-WKZWHVCQSA-N.
Keywords: 2-[2-(4-acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide
Supplier: Cayman Chemical
Supplier-Nr: 16153

Properties

Application: Cell-permeable embryonic stem cell (ESC) pluripotency keeper
MW: 362.4 D
Formula: C21H22N4O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 331001-62-8| Matching products
KEGG ID : K00312 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302
P Phrases: P264, P270, P301+310, P330, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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