Inflachromene

Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay17006-5 5 mg -

6 - 10 business days*

179.00€
Cay17006-10 10 mg -

6 - 10 business days*

284.00€
Cay17006-25 25 mg -

6 - 10 business days*

661.00€
 
Inflachromene is an anti-inflammatory agent that directly binds high mobility group protein 1... more
Product information "Inflachromene"
Inflachromene is an anti-inflammatory agent that directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. It is functional in vivo, downregulating proinflammatory functions of HMGB proteins and reducing neuronal damage. Inflachromene also ameliorates inflammatory pathogenesis in a mouse model of sepsis.Formal Name: 5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione. CAS Number: 908568-01-4. Synonyms: ICM. Molecular Formula: C21H19N3O4. Formula Weight: 377.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS(pH 7.2) (1:4): 0.20 mg/ml, Ethanol: 2.5 mg/ml. lambdamax: 281 nm. SMILES: OC1=CC(OC(C)(C)C2=CCN(C(N(C3=CC=CC=C3)C4=O)=O)N4C25)=C5C=C1. InChi Code: InChI=1S/C21H19N3O4/c1-21(2)16-10-11-22-19(26)23(13-6-4-3-5-7-13)20(27)24(22)18(16)15-9-8-14(25)12-17(15)28-21/h3-10,12,18,25H,11H2,1-2H3. InChi Key: VVOXDJYPDCSQMI-UHFFFAOYSA-N.
Keywords: ICM, 5,12b-dihydro-10-hydroxy-7,7-dimethyl-2-phenyl-1H,7H-[1]benzopyrano[4,3-c][1,2,4]triazolo[1,2-a]pyridazine-1,3(2H)-dione
Supplier: Cayman Chemical
Supplier-Nr: 17006

Properties

Application: Microglial inhibitor
MW: 377.4 D
Formula: C21H19N3O4
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 908568-01-4| Matching products
KEGG ID : K11295 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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