H1152

H1152
Item number Size Datasheet Manual SDS Delivery time Quantity Price
SYN-1221-M001 1 mg -

3 - 9 business days*

106.00€
SYN-1221-M005 5 mg -

3 - 9 business days*

250.00€
SYN-1221-M010 10 mg -

3 - 9 business days*

382.00€
SYN-1221-M050 50 mg -

3 - 9 business days*

-
SYN-1221-M100 100 mg -

3 - 9 business days*

-
 
Solid. Soluble in DMSO. H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK... more
Product information "H1152"
Solid. Soluble in DMSO. H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK inhibitor, with an IC50 of 12nM for ROCKII. H-1152 poorly inhibits PKA, PKC and myosin light chain kinase. Rho kinase (ROCK) activated by GTP-linked Rho phosphorylates targets that are involved in cytoskeletal remodelling, smooth muscle contraction and neuronal development.
Keywords: (S)-4-Methyl-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride, H1152
Supplier: SYNkinase
Supplier-Nr: 1221

Properties

Application: Cell-permeable ROCK inhibitor
MW: 392,3 D
Formula: C16H21N3O2S . 2HCl
Purity: >95%
Format: Solid

Database Information

CAS : 871543-07-6| Find alternatives
KEGG ID : K04514 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +20°C (International: +20°C)
GHS Hazard Pictograms:
H Phrases: H302, H317, H332
Caution
Our products are for laboratory research use only: Not for administration to humans!
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