H1152
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Solid. Soluble in DMSO. H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK... more
Product information "H1152"
Solid. Soluble in DMSO. H-1152 is a potent, specific, ATP-competitive and cell permeable ROCK inhibitor, with an IC50 of 12nM for ROCKII. H-1152 poorly inhibits PKA, PKC and myosin light chain kinase. Rho kinase (ROCK) activated by GTP-linked Rho phosphorylates targets that are involved in cytoskeletal remodelling, smooth muscle contraction and neuronal development.
| Keywords: | (S)-4-Methyl-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline dihydrochloride, H1152 |
| Supplier: | SYNkinase |
| Supplier-Nr: | 1221 |
Properties
| Application: | Cell-permeable ROCK inhibitor |
| MW: | 392,3 D |
| Formula: | C16H21N3O2S . 2HCl |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 871543-07-6| Matching products |
| KEGG ID : | K04514 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +20°C (International: +20°C) |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H317, H332 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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