Gly-Arg-AMC (hydrochloride)

Gly-Arg-AMC (hydrochloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay27580-1 1 mg -

6 - 10 business days*

50.00€
Cay27580-5 5 mg -

6 - 10 business days*

216.00€
Cay27580-10 10 mg -

6 - 10 business days*

379.00€
Cay27580-25 25 mg -

6 - 10 business days*

827.00€
 
Gly-Arg-AMC is a fluorogenic substrate for cathepsin C. Upon enzymatic cleavage by cathepsin C,... more
Product information "Gly-Arg-AMC (hydrochloride)"
Gly-Arg-AMC is a fluorogenic substrate for cathepsin C. Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name: glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, hydrochloride. CAS Number: 70274-78-1. Synonyms: Gly-Arg-7-amino-4-methylcoumarin, GR-AMC, GR-7-amino-4-methylcoumarin. Molecular Formula: C18H24N6O4 . XHCl. Formula Weight: 388.4. Purity: >98%. Emission: 440-460 nm. Excitation: 340-360 nm. Formulation: (Request formulation change), A solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 20 mg/ml. lambdamax: 211, 229, 297, 327 nm. SMILES: O=C1C=C(C)C2=C(C=C(NC([C@@H](NC(CN)=O)CCCNC(N)=N)=O)C=C2)O1. InChi Code: InChI=1S/C18H24N6O4/c1-10-7-16(26)28-14-8-11(4-5-12(10)14)23-17(27)13(24-15(25)9-19)3-2-6-22-18(20)21/h4-5,7-8,13H,2-3,6,9,19H2,1H3,(H,23,27)(H,24,25)(H4,20,21,22)/t13-/m0/s1. InChi Key: JNTASUHAFOHMQK-ZDUSSCGKSA-N.
Keywords: Gly-Arg-7-amino-4-methylcoumarin, GR-7-amino-4-methylcoumarin, GR-AMC, glycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-L-argininamide, hydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 27580

Properties

Application: Fluorogenic cathepsin C substrate
MW: 388.4 D
Formula: C18H24N6O4 . XHCl
Purity: >98%
Format: Solid

Database Information

CAS : 70274-78-1| Matching products
KEGG ID : K01275 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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