GeA-69

GeA-69
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-CR1-3706-M001 1 mg -

3 - 9 business days*

10 %
55.00€
49.50€
 
Off-white to light brownish solid. Soluble in DMSO (2mg/ml). Chemical. CAS: 2143475-98-1.... more
Product information "GeA-69"
Off-white to light brownish solid. Soluble in DMSO (2mg/ml). Chemical. CAS: 2143475-98-1. Formula: C20H16N2O. MW: 300.4. Potent, selective, allosteric inhibitor of macrodomain 2 of poly-adenosine-diphosphate-ribose polymerase 14 (PARP-14 M2) (Kd=0.86µM, ITC (isothermal titration calorimetry) assay). PARP-14 is an anti-apoptotic pro-survival protein associated with inflammatory diseases and several types of cancer. Engages PARP-14 MD2 in intact cells displaces adenosine diphosphate ribose (ADPR) from PARP-14 M2 and prevents recruitment of the PARP-14 M2 to DNA damage sites.
Keywords: N-(2-(9H-Carbazol-1-yl)phenyl)acetamide
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-CR1-3706

Properties

Application: PARP-14 M2 inhibitor
MW: 300,4 D
Formula: C20H16N2O
Purity: >95%
Format: Solid

Database Information

CAS : 2143475-98-1| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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