(±)-Flurbiprofen

(±)-Flurbiprofen
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay70250-1000 1 g -

6 - 10 business days*

32.00€
Cay70250-5000 5 g -

6 - 10 business days*

110.00€
Cay70250-10000 10 g -

6 - 10 business days*

235.00€
Cay70250-25000 25 g -

6 - 10 business days*

313.00€
 
(±)-Flurbiprofen is a non-selective COX inhibitor (IC50s = 0.04 and 0.51 µM for COX-1 and COX-2,... more
Product information "(±)-Flurbiprofen"
(±)-Flurbiprofen is a non-selective COX inhibitor (IC50s = 0.04 and 0.51 µM for COX-1 and COX-2, respectively). In vivo, (±)-flurbiprofen (0.3-4.8 mg/kg, p.o.) reduces carrageenan-induced hind paw edema and yeast-induced fever in rats. (±)-Flurbiprofen reduces plasma fibrinogen levels and arthritic score in a rat model of adjuvant-induced arthritis. It also reduces tumor weight and prostaglandin production and increases survival in a WHT-NC mouse xenograft model when administered at a dose of 5 mg/kg. Formulations containing (±)-flurbiprofen have been used to manage pain and inflammation associated with arthritis. Formal Name: (±)-2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetic acid. CAS Number: 5104-49-4. Synonyms: Ansaid. Molecular Formula: C15H13FO2. Formula Weight: 244.3. Purity: >99%. Formulation: A crystalline solid. Solubility: DMF: 25 mg/ml, DMSO: 10 mg/ml, Ethanol: 25 mg/ml, PBS pH 7.2: .9 mg/ml. lambdamax: 247 nm. SMILES: OC(=O)C(C)c1ccc(c2ccccc2)c(F)c1. InChi Code: InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18). InChi Key: SYTBZMRGLBWNTM-UHFFFAOYSA-N.
Keywords: Ansaid, (±)-2-fluoro-alpha-methyl-[1,1'-biphenyl]-4-acetic acid
Supplier: Cayman Chemical
Supplier-Nr: 70250

Properties

Application: COX inhibitor
MW: 244.3 D
Formula: C15H13FO2
Purity: >99%
Format: Crystalline Solid

Database Information

CAS : 5104-49-4| Find alternatives
KEGG ID : K11987 | Find alternatives

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301
P Phrases: P264, P270, P301+310, P321, P330, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "(±)-Flurbiprofen"
Write a review
or to review a product.
Viewed