Erlotinib hydrochloride

Item number	Size	Manual	Delivery time	Price
SYN-1039-M001	1 mg	-	3 - 9 business days*	66.00€
SYN-1039-M005	5 mg	-	3 - 9 business days*	92.00€
SYN-1039-M010	10 mg	-	3 - 9 business days*	119.00€
SYN-1039-M050	50 mg	-	3 - 9 business days*	158.00€
SYN-1039-M100	100 mg	-	3 - 9 business days*	-

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Soluble in DMSO. Slightly soluble ( 1000-fold more sensitive for EGFR than for c-Src or v-Abl.... more

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Product information "Erlotinib hydrochloride"

Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. Erlotinib inhibits EGFR tyrosine kinase auto-phosphorylation. Studies in cell lines and enzyme assays have shown that erlotinib inhibits EGFR at concentrations significantly lower than those needed to inhibit c-src and v-abl. It has an IC(50) of 2nM against EGFR. It is >1000-fold more sensitive for EGFR than for c-Src or v-Abl. Target: EGFR , Kinase Group: RTK , Substrate: Tyrosine

Keywords:	OSI774, CP-358774, Tarceva, NSC718781
Supplier:	SYNkinase
Supplier-Nr:	1039

Properties

Application:	EGFR inhibitor
MW:	429,9 D
Formula:	C22H23N3O4 . HCl
Purity:	>95%
Format:	Solid

Database Information

CAS :	183319-69-9\| Matching products
KEGG ID :	K04361 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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