Dimethyl Fumarate

Dimethyl Fumarate
Item number Size Datasheet Manual SDS Delivery time Quantity Price
LKT-D3448.25 25 g -

1 - 8 business days

36.00€
LKT-D3448.100 100 g -

1 - 8 business days

100.00€
LKT-D3448.250 250 g -

1 - 8 business days

157.00€
 
Dimethyl fumarate is a fumaric acid methyl ester that is clinically used to treat psoriasis and... more
Product information "Dimethyl Fumarate"
Dimethyl fumarate is a fumaric acid methyl ester that is clinically used to treat psoriasis and under investigation as a potential treatment for multiple sclerosis (MS). Dimethyl fumarate exhibits immunomodulatory, antioxidative, and anti-inflammatory activities. In vitro, dimethyl fumarate increases expression of heme oxygenase 1 (HO-1) and Nrf2 and decreases proliferation of T cells and release of inflammatory cytokines. Dimethyl fumarate activates nicotinic acetylcholine receptors (nAChRs), although the relevance of this activity is unknown. Previously, this compound has been used as a radiosensitizer. Recently, dimethyl fumarate has displayed efficacy in models of multiple sclerosis, decreasing relapse and improving neurologic outcomes.
Keywords: BG-12
Supplier: LKT Laboratories
Supplier-Nr: D3448-25

Properties

Application: Immunomodulator
Purity: >98%
Format: Solid

Database Information

Handling & Safety

Storage: +20°C
Shipping: +20°C (International: +20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H312
P Phrases: P280, P302+352, P312
Caution
Our products are for laboratory research use only: Not for administration to humans!
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