CSF1R / SRE Reporter Kit (MAPK/ERK Signaling Pathway)

CSF1R / SRE Reporter Kit (MAPK/ERK Signaling Pathway)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-79379 500 rxns - -

1 - 15 business days

779.00€
 
The CSF1R SRE Reporter Kit is designed for monitoring the activity of the CSF1R signaling pathway... more
Product information "CSF1R / SRE Reporter Kit (MAPK/ERK Signaling Pathway)"
The CSF1R SRE Reporter Kit is designed for monitoring the activity of the CSF1R signaling pathway in cultured cells. The kit contains a transfection-ready vector for CSF1R and SRE luciferase reporter vector. Upon ligand binding, active CSF1R will initiate the MAPK/ERK signaling pathway, leading to expression of the SRE-controlled reporter. This reporter contains the firefly luciferase gene under the control of multimerized SRE responsive elements located upstream of a minimal promoter. The SRE reporter is premixed with a constitutively-expressing Renilla luciferase vector that serves as an internal control for transfection efficiency. The kit also includes a non-inducible firefly luciferase vector premixed with constitutively- expressing Renilla luciferase vector as a negative control. The non-inducible luciferase vector contains the firefly luciferase gene under the control of a minimal promoter, without any additional response elements. The negative control is critical for determining pathway-specific effects and the background luciferase activity.
Keywords: FMS, CD115, CSF1R, CSF-1R, M-CSF-R, CSF-1-R, EC=2.7.10.1, CSF-1 receptor, Proto-oncogene c-Fms, Macrophage colony-stimulating factor 1 receptor
Supplier: BPS Bioscience
Supplier-Nr: 79379

Properties

Application: Signaling pathway monitoring, , Activator/inhibitor screening, RNAi / gene overexpression studies
Reactivity: Human

Handling & Safety

Storage: Liquid nitrogen
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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