CpG ODN (2216), TLR9 ligand (Class A)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-15-1021-0.1 100 µg - -

3 - 11 business days*

173.00€
ABE-15-1021-1-1 1 mg - -

3 - 11 business days*

576.00€
 
Sequence: 5'-gggggaCGatCGtCGggggg-3' (Class A ODN 2216: Bases are phosphorothioate.) Synthetic... more
Product information "CpG ODN (2216), TLR9 ligand (Class A)"
Sequence: 5'-gggggaCGatCGtCGggggg-3' (Class A ODN 2216: Bases are phosphorothioate.) Synthetic oligodeoxynucleotides (ODN) containing unmethylated deoxycytosine-deoxyguanosine (CpG) motif are equivalent to bacterial DNA in the immunostimulatory activity, which can induce innate immunity via Toll-like receptor 9 (TLR9) in mammals. There are three major classes of CpG ODNs, and each ODN class exhibits different stimulatory effects on immune cell activation. Class A ODNs are potent inducers of IFN-alpha that leads to the plasmacytoid dendritc cell (pDC) maturation. Class B ODNs are relatively weak inducers of type I IFNs but strong stimulators of human B cells and monocyte maturation. Class C ODNs combine elements of both Classes A and B ODNs, which can induce IFN-alpha in pDC and activation of B cells.
Supplier: Abeomics
Supplier-Nr: 15-1021

Properties

Application: Stimulator

Database Information

KEGG ID : K10161 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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