CAY10578

CAY10578
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10011264-1 1 mg -

6 - 10 business days*

17.00€
Cay10011264-5 5 mg -

6 - 10 business days*

74.00€
Cay10011264-10 10 mg -

6 - 10 business days*

130.00€
Cay10011264-25 25 mg -

6 - 10 business days*

285.00€
 
Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction... more
Product information "CAY10578"
Casein Kinase 2 (CK2) is a constitutive protein kinase involved in many signal transduction pathways. CK2 is known to negatively regulate apoptosis, and its activity is increased in many proliferating tissues and tumors, which lends promise as an anticancer drug target. CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, Cdk5, and MSK1). Formal Name: 4,5,6,7-tetraiodo-1,3-dioxo-2-isoindolineacetic acid. CAS Number: 19231-60-8. Molecular Formula: C10H3I4NO4. Formula Weight: 708.8. Purity: >95%. Formulation: A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) 1:5: 0.15 mg/ml, DMSO: 5 mg/ml. lambdamax: 263 nm. SMILES: OC(=O)CN1C(=O)c2c(C1=O)c(I)c(I)c(I)c2I. InChi Code: InChI=1S/C10H3I4NO4/c11-5-3-4(6(12)8(14)7(5)13)10(19)15(9(3)18)1-2(16)17/h1H2,(H,16,17). InChi Key: FLSXICNYHDJIAW-UHFFFAOYSA-N.
Keywords: 4,5,6,7-tetraiodo-1,3-dioxo-2-isoindolineacetic acid
Supplier: Cayman Chemical
Supplier-Nr: 10011264

Properties

Application: CK2 inhibitor
MW: 708.8 D
Formula: C10H3I4NO4
Purity: >95%
Format: Crystalline Solid

Database Information

CAS : 19231-60-8| Find alternatives
KEGG ID : K03097 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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