ASTX660

Item number	Size	Manual	Delivery time	Price
LKT-A744789.1	1 mg	-	3 - 8 business days*	346.00€
LKT-A744789.5	5 mg	-	3 - 8 business days*	1,005.00€
LKT-A744789.25	25 mg	-	3 - 8 business days*	2,765.00€

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ASTX660 is an inhibitor of apoptosis proteins found to target BIR3 domain of cIAP1/2 and XIAP... more

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Product information "ASTX660"

ASTX660 is an inhibitor of apoptosis proteins found to target BIR3 domain of cIAP1/2 and XIAP through a TNFalpha dependent mechanism in melanoma, breast cancer, and lymphoma cell studies. In a breast cancer xenograft model ASTX660 inhibited tumor growth while displaying no significant adverse effects. Treatment of squamous cell carcinoma xenograft models with combination of ASTX660 and radiotherapy showed synergistic effect of delayed tumor growth.

Keywords:	ASTX660, ASTX-660, ASTX 660, Ethanone, 1-(6-((4-fluorophenyl)methyl)-2,3-dihydro-5-(hydroxymethyl)-3,3-dimethyl-1H-pyrrolo(3,2-b)pyridin-1-yl)-2-((2R,5R)-5-methyl-2-(((3R)-3-methyl-4-morpholinyl)methyl)-1-piperazinyl)-
Supplier:	LKT Laboratories
Supplier-Nr:	A744789

Properties

Application:	cIAP / XIAP dual antagonist
MW:	539.7 D
Formula:	C30H42FN5O3
Purity:	>98%
Format:	Solid

Database Information

CAS :	1799328-86-1\| Matching products
KEGG ID :	K16060 \| Matching products

Handling & Safety

Storage:	+20°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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