AG-18

AG-18
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010300-5 5 mg -

6 - 10 business days*

34.00€
Cay10010300-10 10 mg -

6 - 10 business days*

64.00€
Cay10010300-25 25 mg -

6 - 10 business days*

153.00€
Cay10010300-50 50 mg -

6 - 10 business days*

270.00€
 
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases... more
Product information "AG-18"
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. AG-18 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 35 µM in the human epidermoid carcinoma cell line A431. Formal Name: 2-[(3,4-dihydroxyphenyl)methylene]-propanedinitrile. CAS Number: 118409-57-7. Synonyms: RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin AG-18. Molecular Formula: C10H6N2O2. Formula Weight: 186.1. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 381 nm. SMILES: N#CC(=Cc1ccc(O)c(O)c1)C#N. InChi Code: InChI=1S/C10H6N2O2/c11-5-8(6-12)3-7-1-2-9(13)10(14)4-7/h1-4,13-14H. InChi Key: VTJXFTPMFYAJJU-UHFFFAOYSA-N.
Keywords: RG-50810, RG-50858, TX 825, Tyrphostin 23, Tyrphostin AG-18, 2-[(3,4-dihydroxyphenyl)methylene]-propanedinitrile
Supplier: Cayman Chemical
Supplier-Nr: 10010300

Properties

Application: EGF receptor kinase inhibitor
MW: 186.1 D
Formula: C10H6N2O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 118409-57-7| Find alternatives
KEGG ID : K04361 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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