2-deoxy-D-Glucose

2-deoxy-D-Glucose
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay14325-1 1 g -

6 - 10 business days*

68.00€
Cay14325-5 5 g -

6 - 10 business days*

295.00€
Cay14325-10 10 g -

6 - 10 business days*

521.00€
Cay14325-25 25 g -

6 - 10 business days*

1,136.00€
 
2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis. It inhibits... more
Product information "2-deoxy-D-Glucose"
2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis. It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate. 2-deoxy-D-glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B osteosarcoma cells cultured under hypoxic conditions when used at a concentration of 2 mg/ml. In vivo, 2-deoxy-D-glucose (500 mg/kg) reduces tumor growth in 143B osteosarcoma and MV522 non-small cell lung cancer mouse xenograft models when used alone or in combination with doxorubicin (Cay-15007) or paclitaxel (Cay-10461).Formal Name: 2-deoxy-D-arabino-hexose. CAS Number: 154-17-6. Synonyms: Ba 2758, 2-DG, NSC 15193. Molecular Formula: C6H12O5. Formula Weight: 164.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O[C@@H]1[C@@H](CO)OC(O)C[C@H]1O. InChi Code: InChI=1S/C6H12O5/c7-2-4-6(10)3(8)1-5(9)11-4/h3-10H,1-2H2/t3-,4-,5?,6+/m1/s1. InChi Key: PMMURAAUARKVCB-CERMHHMHSA-N.
Keywords: Ba 2758, NSC 15193, 2-deoxy-D-arabino-hexose
Supplier: Cayman Chemical
Supplier-Nr: 14325

Properties

Application: Non-metabolizable glucose analog
MW: 164.2 D
Formula: C6H12O5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 154-17-6| Matching products
KEGG ID : K00844 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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