Tilmicosin-d3

Tilmicosin-d3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay33545-5 5 mg -

6 - 10 business days*

269.00€
 
Tilmicosin-d3 is intended for use as an internal standard for the quantification of tilmicosin... more
Product information "Tilmicosin-d3"
Tilmicosin-d3 is intended for use as an internal standard for the quantification of tilmicosin (Cay-18190) by GC- or LC-MS. Tilmicosin is a macrolide antibiotic. It is active against macrolide-susceptible strains of M. haemolytica, P. multocida, and E. coli (MICs = 4, 4, and 128 µM, respectively), as well as a hyperpermeable strain of E. coli (MIC = 2 µM), and inhibits bacterial protein synthesis (IC50 = 0.36 µM). Tilmicosin (75 mg/kg) increases serum creatine kinase (CK), the MB isoform of CK (CK-MB), and malondialdehyde (MDA) levels in mice, indicating cardiotoxicity. Formulations containing tilmicosin have been used in the treatment of respiratory diseases in sheep and cattle.Formal Name: (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-(methyl(methyl-d3)amino)tetrahydro-2H-pyran-2-yl)oxy)-7-(2-((3S,5R)-3,5-dimethylpiperidin-1-yl)ethyl)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyloxacyclohexadeca-11,13-diene-2,10-dione. Molecular Formula: C46H77D3N2O13. Formula Weight: 872.2. Purity: >99% deuterated forms (d1-d3). Formulation: A solid. Solubility: Chloroform: slightly soluble, Methanol: slightly soluble. SMILES: C[C@@H](C[C@H](C1)C)CN1CC[C@@H](C[C@H](C(/C=C/C(C)=C/[C@@H]([C@H](OC(C[C@H]([C@@H]2C)O)=O)CC)CO[C@H]3[C@@H]([C@@H]([C@@H]([C@H](O3)C)O)OC)OC)=O)C)[C@@H]2O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C)O)N(C)C([2H])([2H])[2H])O. InChi Code: InChI=1S/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1/i9D3. InChi Key: JTSDBFGMPLKDCD-VRFNIZQKSA-N.
Keywords: (4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-3,5-dihydroxy-6-methyl-4-(methyl(methyl-d3)amino)tetrahydro-2H-pyran-2-yl)oxy)-7-(2-((3S,5R)-3,5-dimethylpiperidin-1-yl)ethyl)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyl
Supplier: Cayman Chemical
Supplier-Nr: 33545

Properties

Application: GC-MS, LC-MS internal standard, Quantification, Macrolide antibiotic
MW: 872.2 D
Formula: C46H77D3N2O13
Purity: >99% deuterated forms (d1-d3)
Format: Solid

Database Information

KEGG ID : K01980 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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