Tebipenem (hydrate)

Tebipenem (hydrate)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay33875-100 100 mg - -

6 - 10 business days*

32.00€
Cay33875-250 250 mg - -

6 - 10 business days*

70.00€
Cay33875-500 500 mg - -

6 - 10 business days*

118.00€
Cay33875-1 1 g - -

6 - 10 business days*

157.00€
 
Tebipenem is a carbenapenem antibiotic. It is active against a panel of clinical isolates from a... more
Product information "Tebipenem (hydrate)"
Tebipenem is a carbenapenem antibiotic. It is active against a panel of clinical isolates from a variety of bacterial species (MIC50s = =0.0039-8 µg/ml), including methicillin-resistant strains of S. aureus and S. epidermidis and penicillin-resistant S. pneumoniae. Tebipenem inhibits beta-lactamase in a concentration-dependent manner. It decreases the number of colony forming units (CFUs) in the lungs in a mouse model of penicillin-resistant S. pneumoniae infection when administered at doses ranging from 0.32 to 3.2 mg/kg.Formal Name: (4R,5S,6S)-3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, hydrate. Synonyms: LJC 11,036, SPR859, TBPM. Molecular Formula: C16H21N3O4S2 . XH2O. Formula Weight: 383.5. Purity: >95%. Formulation: A solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 1 mg/ml. lambdamax: 210, 305 nm. SMILES: OC(C1=C(SC2CN(C3=NCCS3)C2)[C@H](C)[C@@]([C@]4([C@H](O)C)[H])([H])N1C4=O)=O.OOC(C1=C(SC2CN(C3=NCCS3)C2)[C@H](C)[C@@]([C@]4([C@H](O)C)[H])([H])N1C4=O)=O.O. InChi Code: InChI=1S/C16H21N3O4S2.H2O/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)25-9-5-18(6-9)16-17-3-4-24-16,/h7-11,20H,3-6H2,1-2H3,(H,22,23),1H2/t7-,8-,10-,11-,/m1./s1. InChi Key: GRHXQHSATFNZQR-PIFQMSPBSA-N.
Keywords: LJC 11,036, SPR859, TBPM, (4R,5S,6S)-3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, hydrate
Supplier: Cayman Chemical
Supplier-Nr: 33875

Properties

Application: Carbenapenem antibiotic, Antibacterial, Cell wall biosynthesis inhibitor
MW: 383.5 D
Formula: C16H21N3O4S2 . XH2O
Purity: >95%
Format: Solid

Database Information

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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