Mitomycin C

Mitomycin C
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay11435-5 5 mg -

6 - 10 business days*

84.00€
Cay11435-10 10 mg -

6 - 10 business days*

123.00€
Cay11435-25 25 mg -

6 - 10 business days*

283.00€
Cay11435-50 50 mg -

6 - 10 business days*

432.00€
 
Mitomycin C (MMC) is an antitumor antibiotic that was discovered as a fermentation product of S.... more
Product information "Mitomycin C"
Mitomycin C (MMC) is an antitumor antibiotic that was discovered as a fermentation product of S. caespitosus. As an alkylating agent, its activity depends on reductive activation either through low pH or DT-diaphorase or NADH cytochrome c reductase. Activated MMC crosslinks double stranded DNA and is widely used as a tool to selectively inhibit DNA synthesis and mutagenensis, to stimulate genetic recombination, chromosome breakage and sister chromatid exchange, and to induce DNA repair. MMC has clinical significance in combination cancer chemotherapy of solid tumors as well as for modulating wound healing after ophthalmological surgeries and in the management of various corneal disorders.Formal Name: 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1aS,2,8S,8aR,8bS-hexahydro-8a-methoxy-5-methyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. CAS Number: 50-07-7. Synonyms: Ametycine, MitoExtra, Mitonco, Mitoplus, MMC, NSC 26980. Molecular Formula: C15H18N4O5. Formula Weight: 334.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 0.1 mg/ml, PBS (pH 7.2): 0.5 mg/ml. lambdamax: 216, 359 nm. SMILES: NC1=C(C)C(C(N(C[C@H]2[C@@H]3N2)[C@@]3(OC)[C@@H]4COC(N)=O)=C4C1=O)=O. InChi Code: InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1. InChi Key: NWIBSHFKIJFRCO-WUDYKRTCSA-N.
Keywords: Ametycine, MitoExtra, Mitonco, Mitoplus, MMC, NSC 26980, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1aS,2,8S,8aR,8bS-hexahydro-8a-methoxy-5-methyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Supplier: Cayman Chemical
Supplier-Nr: 11435

Properties

Application: Antitumor antibiotic
MW: 334.3 D
Formula: C15H18N4O5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 50-07-7| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H300, H310, H330, H351
P Phrases: P201, P202, P260, P262, P264, P270, P271, P280, P284, P301+310, P302+352, P304+340, P308+313, P310, P320, P321, P330, P361+364, P403+233, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Mitomycin C"
Write a review
or to review a product.
Viewed