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Product information "Faropenem (sodium salt hydrate)"
Faropenem is a broad-spectrum penem antibiotic. It is active against a panel of 12 Gram-positive (MIC50s = 0.008-1 mg/L) and 15 Gram-negative (MIC50s = 0.06-16 mg/L) bacteria. Faropenem (20 mg/kg) reduces the number of lung colony forming units (CFUs) in a mouse model of H. influenzae-induced respiratory tract infection. Formulations containing faropenem have been used in the treatment of various bacterial infections.Formal Name: (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, monosodium salt, pentahydrate. CAS Number: 158365-51-6. Molecular Formula: C12H14NO5S . Na [2.5H2O]. Formula Weight: 352.3. Purity: >98%. Formulation: A solid. Solubility: DMF: 1 mg/ml, DMSO: 5 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 263, 304 nm. SMILES: [O-]C(C1=C([C@]2([H])OCCC2)S[C@@]([C@@]3([H])[C@H](O)C)([H])N1C3=O)=O.[O-]C(C4=C([C@]5([H])OCCC5)S[C@@]([C@@]6([H])[C@H](O)C)([H])N4C6=O)=O.[Na+].O.O.O.O.O.[Na+]. InChi Code: InChI=1S/2C12H15NO5S.2Na.5H2O/c2*1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6,,,,,,,/h2*5-7,11,14H,2-4H2,1H3,(H,16,17),,,5*1H2/q,,2*+1,,,,,/p-2/t2*5-,6-,7+,11-,,,,,,,/m11......./s1. InChi Key: MOGICMVNWAUWMK-HIXRZVNASA-L.