Erythromycin

Erythromycin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay16486-5 5 g -

1 - 10 business days

44.00€
Cay16486-10 10 g -

1 - 10 business days

79.00€
Cay16486-25 25 g -

1 - 10 business days

143.00€
Cay16486-100 100 g -

1 - 10 business days

482.00€
 
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the... more
Product information "Erythromycin"
Erythromycin is a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 50S ribosomal subunit, blocking the progression of nascent polypeptide chains. It is active against a host of bacterial genera, including Streptococcus, Staphylococcus, and Haemophilus (MIC90s = 0.015-2.0 mg/l). Erythromycin (10-40 mg/kg) dose-dependently inhibits the growth of S. aureus in a mouse model of thigh infection. It also inhibits the cytochrome P450 (CYP450) isoform CYP3A4 in vitro with IC50 values of 33 and 27.3 µM for alpha-hydroxytriazolam and 4-hydroxytriazolam formation, respectively, following administration of triazolam, which is known to be metabolized primarily by CYP3A4. Formulations containing erythromycin have been used in the treatment of bacterial respiratory and skin infections, pertussis, and a variety of other bacterial infections.
Keywords: Ak-Mycin(R), Eryc(R), NSC 55929, Staticin(R), erythromycin
Supplier: Cayman Chemical
Supplier-Nr: 16486-5

Properties

Application: Antibacterial macrolide antibiotic, Protein synthesis inhibitor (23S rRNA of 50S ribosomal subunit)
MW: 733.9 D
Formula: C37H67NO13
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 114-07-8| Search using CAS
KEGG ID : K01980 | Search using KEGG ID

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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