Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01)

Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2297-39.1 1 mg - -

3 - 19 business days*

549.00€
 
Isolated from Streptomyces sp., Antibiotic UCN-01 inhibits protein kinase C (PKC) and... more
Product information "Antibiotic UCN-01 (7-Hydroxystaurosporine, UCN-01)"
Isolated from Streptomyces sp., Antibiotic UCN-01 inhibits protein kinase C (PKC) and cyclin-dependent kinase 2 (CDK2) resulting in accumulation of cells in the G1 phase and induction of apoptosis. UCN-01 also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by these anti-cancer agents. Solubility: Soluble in ethyl ethanol, DMF or DMSO. , Storage and Stability:, Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Protect from light.
Keywords: Antibiotic
Supplier: United States Biological
Supplier-Nr: A2297-39

Properties

Application: Apoptosis inducer
Formula: C28H26N4O4

Database Information

CAS : 112953-11-4| Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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