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Spiramycin
Item number: LKT-S6232.5
A macrolide antibiotic. It has been shown to decrease the replication index of humanlymphocytes.
| Keywords: | SPM, RP-5337 |
| Application: | Antibiotic, macrolide |
| CAS | 8025-81-8 |
| MW: | 842,05 D |
From 137.00€
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Oligomycin Complex
Item number: Cay11341-5
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. The mitochondrial F1FO ATP synthase can switch to an ATP hydrolase during ischemia, so that, under these conditions, inhibition by oligomycins...
| Application: | ATP synthase inhibitor, Apoptosis inducer |
| CAS | 1404-19-9 |
| MW: | 789,3 D |
From 43.00€
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Mitomycin C
Item number: Cay11435-5
Mitomycin C (MMC) is an antitumor antibiotic that was discovered as a fermentation product of S. caespitosus. As an alkylating agent, its activity depends on reductive activation either through low pH or DT-diaphorase or NADH cytochrome c reductase. Activated MMC crosslinks double stranded DNA and is widely used as...
| Keywords: | Ametycine, MitoExtra, Mitonco, Mitoplus, MMC, NSC 26980,... |
| Application: | Antitumor antibiotic |
| CAS | 50-07-7 |
| MW: | 334.3 D |
From 84.00€
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Gentamycin (Gentamicin) Sulfate Solution 50mg/ml...
Item number: G2032.20
Broad spectrum, cell culture antibiotic that is non toxic to viruses and mammalian cells at antibacterial levels. Inhibits growth of gram positive and negative bacteria, and mycoplasma. Inhibits normal protein synthesis by binding to L6 protein of 50S ribosomal subunit. Useful antibiotic for Baculovirus expression...
| CAS | 1405-41-0 |
From 144.00€
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Actinomycin D
Item number: Cay11421-5
Actinomycin D is a cyclic polypeptide-containing antibiotic that binds to DNA and blocks transcription. It binds to pre-melted double-stranded DNA in transcription bubbles and once bound is slow to dissociate. DNA in transcriptionally hyperactive cancer cells efficiently and rapidly bind actinomycin D at low...
| Keywords: | Cosmegen, Dactinomycin, Meractinomycin, NCI C04682, NSC 3053, Oncostatin K,... |
| Application: | Cancer studies, antineoplastic |
| CAS | 50-76-0 |
| MW: | 1255.5 D |
From 90.00€
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Vancomycin (hydrochloride)
Item number: Cay15327-1
Vancomycin is a glycopeptide antibiotic identified for its utility in the treatment of gram-positive bacteria, including penicillin-resistant staphylococci. It acts by binding to bacterial cell wall protein precursors, interfering with continuing protein synthesis. Vancomycin resistance in staphylococcal species has...
| Keywords: | Lyphocin, Vancomycin hydrochloride |
| Application: | Antibiotic |
| CAS | 1404-93-9 |
| MW: | 1449.3 D |
From 77.00€
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Antibiotic PF 1052
Item number: BVT-0338-M001
Antibiotic, Antibacterial, antifungal and phytotoxic. Isolated from Phoma sp.
| Keywords: | (E)-5-(sec-Butyl)-3-((2-(2,3-dimethyloxiran-2-yl)-6,8-dimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl)(hydroxy)methyle... |
| Application: | Bioassays |
| CAS | 147317-15-5 |
| MW: | 429,6 D |
From 120.00€
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Chloramphenicol (Chloromycetin)
Item number: C4350.1
Chloramphenicol is a chlorine-containing antibiotic produced by Streptomyces venezuelae. It has a wide spectrum of activity against gram-positive and gram-negative cocci and bacilli (including anaerobes), Rickettsia, Mycoplasma, and Chlamydia. It inhibits prokaryotic protein synthesis by attaching to the 50S...
| CAS | 56-75-7 |
| MW: | 323.13 D |
From 75.00€
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Ampicillin (sodium salt)
Item number: Cay14417-25
Ampicillin is a broad-spectrum antibiotic with activity against Gram-positive and Gram-negative bacteria, including veterinary isolates of S. pseudintermedius, S. aureus, E. coli, Pasteurella, and S. canis (MIC50s = 0.25, 0.5, 2, 0.12, and 0.25 µg/ml, respectively). In vivo, ampicillin (80 mg/kg, i.v.) reduces cough...
| Keywords: | (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,... |
| Application: | Antibiotic |
| CAS | 69-52-3 |
| MW: | 371.4 D |
From 58.00€
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GE2270A
Item number: AG-CN2-0303-M001
Isolated from Planobispora rosea. White to off-white powder. Soluble in DMSO or other organic solvents. Thiopeptide antibiotic. Antibacterial agent by inhibiting bacterial protein synthesis. Active against numerous Gram-positive pathogens, including methicillin-resistant strains of Staphylococcus aureus and...
| Keywords: | Antibiotic GE 2270A, MDL 62879 |
| Application: | Thiopeptide antibiotic, EF-Tu inhibitor |
| CAS | 134861-34-0 |
| MW: | 1290.5 D |
From 105.00€
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Rifamycin O
Item number: AG-CN2-0333-M050
Semisynthetic. Beige powder. Soluble in DMSO, aqueous acetonitrile or ethanol. Ansamycin antibiotic. Selective inhibitor of bacterial DNA-dependent RNA polymerase (RNAP). Effective against mycobacteria, and are therefore used in research of tuberculosis, leprosy and mycobacterium avium complex (MAC) infections.
| Keywords: | 4-O-(Carboxymethyl)-1-deoxy-1,4-dihydro-4-hydroxy-1-oxo-rifamycin gamma-lactone, NSC 182391 |
| Application: | Antibiotic, Bacterial DNA-dependent RNA polymerase inhibitor |
| CAS | 14487-05-9 |
| MW: | 753.8 D |
From 83.00€
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Cefpirome (sulfate)
Item number: Cay37398-1
Cefpirome is a cephalosporin antibiotic. It is active against clinical isolates of various bacteria, including K. pneumoniae, E. aerogenes, Salmonella, and Shigella (MIC50s = 0.06, 0.12, 0.06, and 0.06 µg/ml, respectively). Cefpirome protects non-leukopenic mice from systemic bacterial infections induced by E. coli,...
| Keywords: | HR 810,... |
| Application: | Cephalosporin antibiotic, antibacterial, cell wall biosynthesis inhibitor |
| CAS | 98753-19-6 |
| MW: | 612.7 D |
From 35.00€
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