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Mcl-1 inhibitor 12
Item number: TGM-T75143-50mg
Description: Mcl-1 Inhibitor 12 (Example 10), with a K i of 0.22 nM, functions as an MCL-1 inhibitor. It is utilized in cancer research [1]. Target: Others
| Application: | Mcl-1 inhibitor |
| CAS | 2445466-24-8 |
| MW: | 858.35 D |
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TRV-7019
Item number: TGM-T75145-2mg
Description: TRV-7019 is a butyrylcholinesterase-targeting radioligand capable of penetrating the blood-brain barrier (BBB) for brain imaging. It is utilized for diagnosing conditions such as amyloid diseases, multiple sclerosis, brain tumors, or to assess butyrylcholinesterase activity [1]. Target: Others
| CAS | 2598164-15-7 |
| MW: | 369.15 D |
61.00€
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PROTAC BRD4 Degrader-19
Item number: TGM-T75149-50mg
Description: PROTAC BRD4 Degrader-19 (compound 176) is a proteolysis-targeting chimera (PROTAC) developed to specifically degrade the BRD4 protein, potentially useful in cancer research [1]. Target: PROTACs
| CAS | 2684292-71-3 |
| MW: | 822.95 D |
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GIP/GLP-1 dual receptor agonist-1
Item number: TGM-T75150-50mg
Description: GIP/GLP-1 dual receptor agonist-1 (compound 4), a receptor agonist for both GIP and GLP-1, shows potential for researching metabolic disorders and fatty liver diseases, such as nonalcoholic steatohepatitis (NASH) and nonalcoholic fatty liver disease (NAFLD) [1]. Target: Others
| CAS | 2807481-02-1 |
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ARC19499
Item number: TGM-T75152-50mg
Description: ARC19499, an aptamer, inhibits the tissue factor pathway inhibitor (TFPI), facilitating clot initiation and propagation through the extrinsic pathway. It binds specifically to TFPI, blocking its inhibition of both factor Xa and the TF/factor VIIa complex, thereby correcting thrombin generation in...
| CAS | 1350667-54-7 |
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ATU027
Item number: TGM-T75154-50mg
Description: ATU027, a small interfering RNA (siRNA), silences protein kinase N3 (PKN3) expression in the vascular endothelium. It has been demonstrated to thwart local tumor invasion, as well as lymph node and pulmonary metastasis, in mouse cancer models. Target: Others
| CAS | 1415935-22-6 |
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Bamosiran
Item number: TGM-T75155-50mg
Description: Bamosiran, a small interfering RNA (siRNA), specifically targets the beta-adrenergic receptor 2 to reduce intraocular pressure. Target: Others
| CAS | 1337968-84-9 |
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Bevasiranib
Item number: TGM-T75156-50mg
Description: Bevasiranib, a siRNA, is specifically engineered to suppress the expression of genes responsible for the production of vascular endothelial growth factor (VEGF), a critical factor in the development of choroidal neo-vascularization (CNV), which precedes wet age-related macular degeneration (wet AMD)....
| CAS | 959961-96-7 |
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SARS-CoV-2-IN-47
Item number: TGM-T78719-50mg
Description: SARS-CoV-2-IN-47 (Compound 13), with IC50 values of 0.77 µM against Omicron BA.1 and 0.93 µM against the Delta strain, acts as an inhibitor of SARS-CoV-2 and is used in antiviral research [1]. Target: SARS-CoV
| MW: | 527.65 D |
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SARS-CoV-2-IN-48
Item number: TGM-T78720-50mg
Description: SARS-CoV-2-IN-48 (compound 19) is an inhibitor of SARS-CoV-2, with an IC50 of 2.7 µM against the Omicron BA.1 variant and demonstrating antiviral activities [1]. Target: SARS-CoV
| MW: | 463.48 D |
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ZINC475239213
Item number: TGM-T78722-100mg
Description: ZINC475239213 acts as an inhibitor targeting the SARS-CoV-2 Nsp14 N7-Methyltransferase with an IC50 value of 20 µM [1]. Target: SARS-CoV
| CAS | 2871002-89-8 |
| MW: | 369.38 D |
From 1,440.00€
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ZINC61142882
Item number: TGM-T78723-50mg
Description: ZINC61142882 is a SARS-CoV-2 Nsp14 N7-Methyltransferase inhibitor with an IC50 value of 6 µM [1]. Target: SARS-CoV
| MW: | 387.19 D |
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