Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)

Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)
Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)
Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)
Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)
Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)
COVID-19 Research
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-79942-1 100 µl (100 µl) - -

3 - 15 business days*

998.00€
BPS-79942-2 1 ml (500 µl x 2) - -

3 - 15 business days*

4,752.00€
 
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome... more
Product information "Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)"
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting Enzyme 2 (ACE2) receptor found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. Drugs targeting the interaction between the Spike protein of SARS-CoV-2 and ACE2 may offer protection against the viral infection. The SARS-CoV-2 Spike Pseudotyped Lentivirus were produced with SARS-CoV-2 Spike (Genbank Accession #QHD43416.1) as the envelope glycoproteins instead of the commonly used VSV-G. These pseudovirions also contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be conveniently measured via luciferase reporter activity. The SARS-CoV-2 Spike pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 in a Biosafety Level 2 facility.
Keywords: 2
Supplier: BPS Bioscience
Supplier-Nr: 79942-1

Properties

Application: Viral transduction studies, Neutralizing SARS-CoV-2 Spike antibodies screening
Reactivity: Sars-cov-2

Database Information

UniProt ID : P0DTC2 | Find alternatives

Handling & Safety

Storage: -80°C (avoid repeat freezing and thawing cycles)
Shipping: -80°C (International: -80°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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