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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-60655 | 2 vials (2 vials) | - | - |
3 - 15 business days* |
12,905.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The Glucocorticoid Receptor Pathway GAL4 Reporter (Luc) - HEK293 Cell Line contains a firefly... more
Product information "GAL4 Reporter (Luc)-HEK293 cell Line (Glucocorticoid Receptor Pathway)"
The Glucocorticoid Receptor Pathway GAL4 Reporter (Luc) - HEK293 Cell Line contains a firefly luciferase gene under the control of glucocorticoid receptor ligand binding domain that is fused to the DNA binding domain (DBD) of GAL4 (GAL4 DBD-GR) stably integrated into HEK293 cells. This fusion construct activates firefly luciferase expression under the control of a multimerized GAL4 upstream activation sequence (UAS). This allows for specific detection of glucocorticoid-induced activation of the glucocorticoid receptor without the need for individual transcriptional targets and with low cross-reactivity for other nuclear receptor pathways. This cell line is validated for response to stimulation of dexamethasone and to the treatment with mifepristone, an inhibitor of the glucocorticoid signaling pathway.
Keywords: | GAL4, Glucocorticoid Receptor, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 60655 |
Properties
Application: | Monitor glucocorticoid signaling pathway activity, screening |
Host: | human cells |
Species reactivity: | human |
Database Information
KEGG ID : | K05771 | Matching products |
UniProt ID : | P04150 | Matching products |
Gene ID | GeneID 2908 | Matching products |
Handling & Safety
Storage: | Liquid nitrogen (store in liquid nitrogen) |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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