Thromboxane B2 ELISA Kit

Thromboxane B2 ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay501020-96S 96 so-wells (96 solid wells) -

1 - 10 business days

357.00€
Cay501020-96 96 st-wells (96 strip wells) -

approx. 1-3 business days

357.00€
Cay501020-480S 480 so-wells (480 solid wells) -

1 - 10 business days

1,332.00€
Cay501020-480 480 st-wells (480 strip wells) -

1 - 10 business days

1,332.00€
 
Thromboxane A2 (TXA2) is produced from arachidonic acid by many cells and causes irreversible... more
Product information "Thromboxane B2 ELISA Kit"
Thromboxane A2 (TXA2) is produced from arachidonic acid by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle. Like most lipid mediators, TXA2 is not a circulating hormone. It is formed in response to local stimuli and exerts its effects within a short distance of its biosynthesis. TXA2 is rapidly hydrolyzed non-enzymatically to form TXB2, which is then quickly metabolized (t½ = 5-7 minutes) to urinary metabolites for clearance by the kidneys. Because of the transient nature of this compound it is difficult to accurately measure circulating levels in whole animal experimental models. In fact, it has been shown that plasma and urine levels of TXB2 are primarily due to ex vivo platelet activation and intra-renal production, respectively. Therefore, measurement of TXB2 metabolites, such as 11-dehydro TXB2 (Cay-519510), in urine and plasma may give more accurate estimates of in vivo TXA2 production. TXB2 measurement is better suited for samples that are unlikely to undergo extensive metabolism such as perfusates, lavage samples, tissue/cell culture, etc.
Keywords: TXB2 EIA Kit
Supplier-Nr: 501020-96S

Properties

Application: ELISA
Format: Solid Phase

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H302, H311, H315, H317, H318, H319, H335, H351, H361
P Phrases: P201, P202, P261, P264, P270, P271, P272, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P332+P313, P333+P313, P337+P313, P361+P364, P362+P364, P405, P403+P233, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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