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Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG82111.96 | 96 wells | - |
6 - 14 business days* |
1,048.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF,... more
Product information "Rat CD130 / gp130 ELISA Kit"
Protein function: Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates Janus kinases. That causes phosphorylation of IL6ST tyrosine residues which in turn activates STAT3. Mediates signals which regulate immune response, hematopoiesis, pain control and bone metabolism. Has a role in embryonic development. Does not bind IL6. Essential for survival of motor and sensory neurons and for differentiation of astrocytes. Required for expression of TRPA1 in nociceptive neurons. Required for the maintenance of PTH1R expression in the osteoblast lineage and for the stimulation of PTH-induced osteoblast differentiation. Required for normal trabecular bone mass and cortical bone composition. [The UniProt Consortium]
| Keywords: | Il6st, CD130, gp130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta, Interleukin-6 signal transducer, Interleukin-6 receptor subunit beta, Oncostatin-M receptor subunit alpha |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG82111 |
Properties
| Application: | ELISA |
| Species reactivity: | rat |
| Format: | Solid Phase |
Database Information
| UniProt ID : | P40190 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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