Prostaglandin F2alpha ELISA Kit

Prostaglandin F2alpha ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay516011-96S 96 so-wells (96 solid wells) -

1 - 10 business days

357.00€
Cay516011-96 96 st-wells (96 strip wells)

1 - 10 business days

357.00€
Cay516011-480 480 st-wells (480 strip wells)

1 - 10 business days

1,337.00€
Cay516011-480S 480 so-wells (480 solid wells) -

1 - 10 business days

1,337.00€
 
Prostaglandin F2alpha (PGF2alpha) is one of the five primary PGs derived enzymatically directly... more
Product information "Prostaglandin F2alpha ELISA Kit"
Prostaglandin F2alpha (PGF2alpha) is one of the five primary PGs derived enzymatically directly from the endoperoxide PGH2. It was initially discovered in seminal fluid, and to date the majority of the functional roles ascribed to it relate to fertility, pregnancy, and parturition. PGF2alpha is a potent luteolytic agent and is used to induce ovulation in domestic livestock. It is also a potent uterine stimulant, and is part of the cascade of myometrial stimulants which induce and sustain labor. PGF2alpha is rapidly metabolized to 13,14-dihydro-15-keto PGF2alpha in vivo, and the levels of this metabolite in both plasma and amniotic fluid are elevated during active labor in several different mammalian species. Like all of the primary PGs, PGF2alpha. has a very short half-life in the general circulation. The plasma concentration of PGF2alpha in humans is 2 pg/ml. PGF2alpha is rapidly metabolized by 15-hydroxy PG dehydrogenase and both beta- and omega-oxidation systems to a variety of polar metabolites. In primary cultures, the metabolism of PGF2alpha is much more limited, and it may collect in the supernatant medium to easily measured concentrations. Amnionic and placental tissue PGF2alpha content in the range from 100-250 ng/g of tissue has been reported. However, this study did not address the presence of isoprostanes and reported measurements using an unvalidated RIA method. A controlled GC- or LC-MS study of tissue PG content has not been reported. Tissue PG measurements in general are difficult to perform, vary widely, and are challenging to interpret.
Keywords: PGF2alpha EIA Kit
Supplier-Nr: 516011-96S

Properties

Application: ELISA
Format: Solid Phase

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H302, H312, H335, H350, H360
P Phrases: P201, P202, P210, P240, P241, P242, P243, P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P332+P313, P337+P313, P361+P364, P370+P378, P405, P403+P233, P403+P235, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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