Mouse 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit

Mouse 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-EL-M1279.96 96 wells - -

7 - 16 business days

587.00€
 
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of 12-LO in serum,... more
Product information "Mouse 12-LO (Arachidonate 12-Lipoxygenase) ELISA Kit"
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of 12-LO in serum, plasma and other biological fluids. Detection Range: 0.78--50ng/mL. Sensitivity: 0.47ng/mL. Protein function: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)- hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation. [The UniProt Consortium]
Keywords: Alox12, P-12LO, 12S-LOX, Alox12p, EC=3.3.2.-, EC=1.13.11.31, 12S-lipoxygenase, Lipoxin synthase 12-LO, Platelet-type lipoxygenase 12, Arachidonate 12-lipoxygenase, 12S-type
Supplier: Elabscience
Supplier-Nr: E-EL-M1279

Properties

Application: ELISA
Reactivity: Mouse
Format: Solid Phase

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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