Human IgG4 (Immunoglobulin G4) ELISA Kit

Human IgG4 (Immunoglobulin G4) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-EL-H1749.96 96 wells - -

7 - 17 business days

455.00€
 
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of IgG4 in serum,... more
Product information "Human IgG4 (Immunoglobulin G4) ELISA Kit"
The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of IgG4 in serum, plasma and other biological fluids. Detection Range: 7.81--500ng/mL. Sensitivity: 4.69ng/mL. Protein function: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). [The UniProt Consortium]
Keywords: Ig gamma-4 chain C region, Immunoglobulin heavy constant gamma 4
Supplier: Elabscience
Supplier-Nr: E-EL-H1749

Properties

Application: ELISA
Reactivity: Human
Format: Solid Phase

Database Information

UniProt ID : P01861 | Search using UniProt ID

Handling & Safety

Storage: vT
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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