DNA/RNA Oxidative Damage ELISA Kit

DNA/RNA Oxidative Damage ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay589320-96S 96 so-wells (96 solid wells) -

1 - 10 business days

Cay589320-96 96 st-wells (96 strip wells)

approx. 1-3 business days

Cay589320-480 480 st-wells (480 strip wells)

1 - 10 business days

Cay589320-480S 480 so-wells (480 solid wells) -

1 - 10 business days

Both DNA and RNA are damaged by oxidation during aging and in a variety of disease states... more
Product information "DNA/RNA Oxidative Damage ELISA Kit"
Both DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. The repair processes that are initiated to correct this damage release multiple oxidized guanine species into the urine. Cayman Chemical has developed this immunoassay for the measurement of DNA/RNA oxidative damage that detects all three oxidized guanine species, 8-hydroxy-2'-deoxyguanosine from DNA, 8-hydroxyguanosine from RNA, and 8-hydroxyguanine from either DNA or RNA. Some commercial vendors offer immunoassays that detect only 8-hydroxy-2'-deoxyguanosine, and not the other two molecules. The advantage of the Cayman kit is that it captures a more complete set of biologically relevant products of oxidative damage than do assays that are restricted to analysis of only 8-hydroxy-2'-deoxyguanosine. However, because Cayman's kit recognizes more than 8-hydroxy-2'-deoxyguanosine, it is not valid to compare the results from the Cayman ELISA Kit to an LC/MS analysis of 8-hydroxy-2'-deoxyguanosine. The ELISA value will always be significantly higher than LC/MS because the ELISA also detects 8-hydroxyguanosine and 8-hydroxyguanine.
Keywords: 8-hydroxy-2'-Deoxyguanosine, 8-OH-2dG, 8-OH-DG, DNA/RNA Oxidative Damage ELISA Kit
Supplier-Nr: 589320-96S


Application: ELISA
Format: Solid Phase

Database Information

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H225, H301, H302, H311, H315, H317, H318, H319, H335, H336, H351, H361, H372
P Phrases: P201, P202, P210, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P280, P312, P314, P321, P330, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P332+P313, P333+P313, P337+P313, P361+P364, P362+P364, P370+P378, P405, P403+P233, P403+P235, P501
Our products are for laboratory research use only: Not for administration to humans!
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