Csk (Phospho-Ser364) Colorimetric Cell-Based ELISA Kit

Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CBCAB00228.96 96 assays (2 x 96-well microplates) - -

9 - 20 business days*

641.00€
 
Csk (Phospho-Ser364) Colorimetric Cell-Based ELISA Kit Protein function: Non-receptor... more
Product information "Csk (Phospho-Ser364) Colorimetric Cell-Based ELISA Kit"
Csk (Phospho-Ser364) Colorimetric Cell-Based ELISA Kit Protein function: Non-receptor tyrosine-protein kinase that plays an important role in the regulation of cell growth, differentiation, migration and immune response. Phosphorylates tyrosine residues located in the C- terminal tails of Src-family kinases (SFKs) including LCK, SRC, HCK, FYN, LYN, CSK or YES1. Upon tail phosphorylation, Src-family members engage in intramolecular interactions between the phosphotyrosine tail and the SH2 domain that result in an inactive conformation. To inhibit SFKs, CSK is recruited to the plasma membrane via binding to transmembrane proteins or adapter proteins located near the plasma membrane. Suppresses signaling by various surface receptors, including T-cell receptor (TCR) and B-cell receptor (BCR) by phosphorylating and maintaining inactive several positive effectors such as FYN or LCK. [The UniProt Consortium]
Keywords: CSK, C-Src kinase, Tyrosine-protein kinase CSK, Protein-tyrosine kinase CYL
Supplier: Assay Genie
Supplier-Nr: CBCAB00228

Properties

Application: In-cell ELISA

Database Information

KEGG ID : K05728 | Matching products
UniProt ID : P41240 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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