Citrullinated Histone H3 (Clone 11D3) ELISA Kit

Citrullinated Histone H3 (Clone 11D3) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay501620-96 96 wells -

6 - 10 business days*

619.00€
 
Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17... more
Product information "Citrullinated Histone H3 (Clone 11D3) ELISA Kit"
Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore during the process of NETosis, and can be freed from NETs by treatment with nuclease. The measurement of CitH3, either in cell lysates or released during NETosis can be used as a functional readout of pharmacological PAD inhibition. Synonyms: CitH3 (Clone 11D3) EIA Kit. Clone Designation: 11D3. Limit of Detection: 0.1 ng/ml. Assay Range: 0.15-10 ng/ml. Lower Limit of Quantification: 0.3 ng/ml. Origin: Animal/Bovine, Animal/Mouse.
Keywords: CitH3 (Clone 11D3) EIA Kit
Supplier: Cayman Chemical
Supplier-Nr: 501620

Properties

Application: ELISA
Clone: 11D3
Format: Solid Phase

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H315
P Phrases: P264, P280, P302+352, P321, P332+313, P362+364
Caution
Our products are for laboratory research use only: Not for administration to humans!
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