C-Reactive Protein (human) ELISA Kit

C-Reactive Protein (human) ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10011236-96 96 wells -

6 - 10 business days*

C-Reactive Protein (CRP) is a 224 amino acid protein that is synthesized primarily by... more
Product information "C-Reactive Protein (human) ELISA Kit"
C-Reactive Protein (CRP) is a 224 amino acid protein that is synthesized primarily by hepatocytes, and to a lesser extent adipocytes. CRP plasma levels increase ~1,000-fold in response to acute and chronic inflammatory conditions, making it a useful gauge of inflammation in a wide range of physiological and pathological conditions. Normal levels of serum CRP (0.64 µg/ml) do not differ between healthy adult men and women, but tend to increase slightly with age. High plasma CRP concentrations (>3 µg/ml) are associated with an increased risk for atherosclerosis. CRP has been implicated as a contributor to atherogenesis by modulating endothelial function, stimulating coagulation, inducing the expression of ICAM-1, VCAM-1, and E-selectin, mediating uptake of LDL into macrophages, and destabilizing plaques. In addition, CRP can bind in a calcium-dependent manner to phosphocholine on microbes, act as a ligand for specific receptors on phagocytic leukocytes, mediate activation of monocytes and macrophages via IL-6, TNF-alpha and other cytokines, and assist in the complement pathway. Cayman's CRP (human) ELISA Kit is an immunometric assay which can be used to measure CRP in plasma without prior sample purification. The standard curve spans the range of 46.9-3,000 pg/ml with a limit of detection of approximately 46.9 pg/ml. Synonyms: CRP (human) EIA Kit. Limit of Detection: 46.9 pg/ml. Assay Range: 46.9-3,000 pg/ml.
Keywords: CRP (human) EIA Kit
Supplier: Cayman Chemical
Supplier-Nr: 10011236


Application: ELISA
Reactivity: Human
Format: Solid Phase

Database Information

KEGG ID : K16143 | Find alternatives
UniProt ID : P02741 | Find alternatives

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H301, H311, H314, H315, H317, H319, H331, H412
P Phrases: P260, P261, P264, P270, P271, P272, P273, P280, P301+310, P301+330+331, P302+352, P303+361+353, P304+340, P305+351+338, P310, P311, P312, P321, P330, P332+313, P333+313, P337+313, P361+364, P362+364, P363, P403+233, P405, P501
Our products are for laboratory research use only: Not for administration to humans!
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