Anti-Citrullinated Human Fibrinogen Assay Kit (mouse)

Anti-Citrullinated Human Fibrinogen Assay Kit (mouse)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay501270-96 96 wells -

6 - 10 business days*

719.00€
 
Immunization of mice with citrullinated human fibrinogen, especially mice expressing the human... more
Product information "Anti-Citrullinated Human Fibrinogen Assay Kit (mouse)"
Immunization of mice with citrullinated human fibrinogen, especially mice expressing the human HLA-DR4 transgene, induces an arthritic response driven by the production of antibodies that recognize citrullinated epitopes. The polyclonal antibody response produces antibodies reactive with both citrullinated human fibrinogen and unmodified, noncitrullinated human fibrinogen. Cayman's Anti-Citrullinated Human Fibrinogen Assay (mouse) is an immunometric (sandwich) assay that can be used to distinguish the antibody response to citrullinated human fibrinogen from the antibody response to unmodified human fibrinogen in mouse serum or plasma. A human fibrinogen affinity sorbent is provided with the kit so that any antibodies capable of reacting with non-citrullinated (unmodified) fibrinogen can be removed prior to analysis of the remaining anti-citrullinated fibrinogen antibodies for an accurate analysis of the anti-citrulline response. This kit uses a citrullinated human fibrinogen-coated plate and a detection antibody recognizing mouse IgG. An anti-citrullinated human fibrinogen monoclonal antibody is included as a standard. The standard curve spans the range of 0.15 to 10 µg/ml, with an an LLOQ of 0.15 µg/ml. Assay Range: 0.15-10 µg/ml. Lower Limit of Quantification: 0.15 µg/ml. Origin: Animal/Bovine, Animal/Goat, Animal/Mouse.
Keywords: FGA, Citrullination
Supplier: Cayman Chemical
Supplier-Nr: 501270

Properties

Application: ELISA
Format: Solid Phase

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H312, H315, H319, H332, H372
P Phrases: P260, P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P314, P321, P330, P332+313, P337+313, P361+364, P362+364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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