Adiponectin (human) BioAssay(TM) ELISA Kit (ACRP30, AdipoQ, apM1, GBP28, Adipocyte complement relate

Adiponectin is a promising biomarker of insulin resistance and type 2 diabetes mellitus (T2DM) but also as a potential target for management of the metabolic syndrome. It is a very robust marker that is not prone to degradation or acute inflammatory challenges, is present in relatively high concentrations in the peripheral circulation, and can be collected by a variety of methods. The benefits of using adiponectin assays in clinical settings include, (a) prediction of risk of diabetes and metabolic status and (b) providing a tool to monitor metabolic improvements. Adiponectin exerts anti-atherogenic and anti-inflammatory properties and may be important as a biomarker for obesity-related cardiovascular disease (CVD). New findings showed urinary adiponectin excretion as an independent new biomarker of microvascular and macrovascular damage in T2DM and suggested it as a very promising tool for early cardiovascular disease risk assessment. Adiponectin serum level was also described as a good biomarker of colorectal adenoma, this being related to the positive correlation between obesity and increased risk of cancer at various sites (colorectal, breast, prostate and endometrium). Kit Components: 044468A: Microtiter Strips, 1x96 wells, 044468B: Wash Buffer, 10X, 2x30ml, 044468C: ELISA Buffer, 10X, 2x30ml, 044468D: Detection Antibody, 1x30ul, 044468E: HRP, 100X, 1x150ul, 044468F: Adiponectin Standard. 1x1vial, 044468G: TMB Solution, 1x12ml, 044468H: Stop Solution (Sulfuric Acid), 1x12ml, Storage and Stability: Store components at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.